Current Research

Advancing the frontier of psychedelic science

Separating Therapeutic Effects from Hallucinations

Groundbreaking research identifies distinct neural circuits for anxiety reduction versus perceptual effects, potentially enabling therapeutic benefits without intense hallucinations.

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Expanding Psychedelic Applications Beyond Depression

Major institutions launch trials for opioid addiction, Alzheimer's, PTSD, anorexia nervosa, Parkinson's, chronic pain, and post-treatment Lyme disease syndrome.

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Understanding Psychedelic-Induced Brain Changes

New insights into how psychedelics promote structural, functional, and molecular neuroplasticity, with effects persisting weeks after a single dose.

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5-MeO-DMT Shows Promise for Treatment-Resistant Depression

Phase 2b trial demonstrates significant depression score reductions and high remission rates with tolerable side effects in TRD patients.

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Bretisilocin: A Novel Serotonergic Psychedelic

DMT-related compound in Phase 2 trials shows high remission rates for major depressive disorder, attracting major pharmaceutical investment.

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DLX-159: Psychoplastogen Without Perceptual Effects

Delix Therapeutics develops rapidly-acting antidepressant that promotes neuroplasticity without hallucinogenic properties in preclinical models.

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Long-Term Benefits of Psilocybin in Cancer Patients

Single psilocybin session produces years-long improvements in depression and anxiety for cancer patients, with many requiring no further treatment.

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Pharmaceutical Investment and FDA Challenges

Major pharmaceutical deals signal industry confidence while regulatory concerns about data and ethics continue to shape the approval landscape.

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